P-1440. Low measles seroprotection among adults with perinatally acquired HIV

Abstract Background Due to decreasing vaccination rates in the US, there is widespread concern for the reestablishment of measles endemicity. Those with immune suppression, including people living with HIV (PLHIV), would be particularly vulnerable to poor measles-related outcomes. Among young adults living with HIV, rates of measles vaccine-related seroprotection are poorly understood. Critically, adults with perinatally-acquired HIV (PHIV) may be at increased risk of poor measles vaccine seroresponse. We sought to examine patterns of measles vaccination as well as measles vaccine seroresponse among a cohort of young adult PHIV and age-range matched young adults with non-perinatally acquired HIV (NPHIV).Table 1:Cohort demographic and clinical characteristics*p