P-1536. Prevalence and Characteristics of Escherichia coli Sequence Type 131 Isolated from Children with Urinary Tract Infections

Abstract Background Escherichia coli (E.coli) is one of the most common causative pathogen of urinary tract infections in children. Antimicrobial resistance of E. coli has been and is continuing to increase globally. Sequence type (ST) 131 has emerged as a multidrug-resistant (MDR) pathogen. ST131 E. coli isolates have higher virulence than non-ST131 isolates. We aimed to characterize ST131 E. coli isolates from Korean children with UTIs compared to non-ST131 isolates and assess changes in their prevalence since 2011–2014.Antimicrobial susceptibility, ST131 vs. non-ST131 Escherichia coliST131 isolates exhibited significantly lower susceptibility than non-ST131 isolates to amoxicillin/clavulanate, cefotaxime, cefazolin, cefepime, gentamicin, ciprofloxacin, and trimethoprim/sulfamethoxazole (all P