P-1809. Trends in vaccination and diagnostic testing for SARS-CoV-2 and influenza across the United States, 2019 – 2024

Abstract Background To assess trends in SARS-CoV-2 and influenza virus testing and positivity rates in populations administered seasonal vaccines.Change in yearly testing volumes for SARS-CoV-2 and influenza in adult and pediatric populationsMonthly vaccination to testing volumes of SARS-CoV-2 and influenza in adult and pediatric populations Methods We retrospectively reviewed 604,977 vaccination events and 881,573 tests for SARS-CoV-2 and 4,958,425 vaccination events and 31,274 tests for influenza from 2019 to 2024 in a US population administered seasonal vaccines with respiratory diagnostic testing performed at Labcorp. Monthly vaccination volume to testing volume ratio (mVTR) was used to estimate integration of vaccinations and diagnostic testing in health service systems.Breakthrough infection rates for SARS-CoV-2 and influenza by ageComparisons of breakthrough infection rates between