Clinical Characteristics of Patients With Patent Foramen Ovale and Pyogenic Brain Abscess

Open Forum Infectious Diseases 2026 Open access

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Authors: Khalid Abu-Zeinah, Pansachee Damronglerd, Hussam Tabaja, Zachary A. Yetmar, Mark J. Enzler, Guy S. Reeder, Daniel Christopher DeSimone, L.M. Baddour, Omar Abu Saleh, Cristina Corsini Campioli, Supavit Chesdachai
DOI: 10.1093/ofid/ofag026
Cited by: 0
References: 20

Abstract

Patent foramen ovale (PFO) has a prevalence of approximately 25%. Its association with pyogenic brain abscess (PBA) is unclear. We reviewed adults with PBA and known PFO status from 1 January 2009 through 31 December 2021 at Mayo Clinic. High PFO prevalence (40.5%) was seen. PBA patients with PFO had distinct abscess characteristics but unchanged 1-year, all-cause mortality.

Fields of Study & Subjects

Cardiovascular and Diving-Related Complications Infectious Diseases and Tuberculosis Infective Endocarditis Diagnosis and Management

Publication details

Journal / source
Open Forum Infectious Diseases
Volume
13
Issue
2
Pages
ofag026–ofag026
Publication date
14 January 2026
Language
EN