Ivory vertebra: a rare skeletal manifestation of POEMS syndrome
Abstract
21-year-old female with lower motor neuron type weakness of both lower limbs, starting distally and progressing to proximal involvement with sensory loss and severe weight loss over 8 months. On examination, there was pallor, palm, leg, and foot hyperpigmentation were present. Abdominal examination showed hepatomegaly. Nervous system examination revealed bilateral papilledema, lower limb MRC 4/5 motor power, deep tendon reflexes areflexia, and peripheral nerve pattern sensory loss. On investigation, hemoglobin was 12.6 gm/dl and platelets 2.8 × 105/cumm. Serum calcium was 8.6 mg/dl (9–11). On renal function test, serum creatinine was 1 mg/dl (
Fields of Study & Subjects
Peripheral Neuropathies and Disorders
Multiple Sclerosis Research Studies
Hereditary Neurological Disorders
Publication details
- Journal / source
- QJM
- Publisher
- Oxford University Press (OUP)
- Volume
- 119
- Issue
- 8
- Pages
- 627-628
- Publication date
- 15 January 2026
- Language
- EN