Comparison of disease severity and activity between juvenile- and adult-onset dermatomyositis: a multicentre cohort study

Lara D. Veeken 2026

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Authors: A. Sinnaeve, Brigitte Bader-Meunier, Anne Mirguet, T. Moulinet, I. Lemelle, A.‐C. Bursztejn, Joëlle Terzic, Ariane Zaloszyc, Alain Meyer, Thierry Martin, Claire Ballot-Schmit, Julien Campagne
+5 more Loïs Bolko, Bernard Bonnotte, R. Jaussaud, Olivier Benveniste, Paul A. Decker
DOI: 10.1093/rheumatology/keag032
Cited by: 1
References: 39

Abstract

OBJECTIVES: To compare the severity at diagnosis and disease activity during follow-up between juvenile (jDM) and adult-onset (aDM) dermatomyositis. METHODS: Patients with DM fulfilling the 2017 ACR/EULAR criteria and tested for myositis-specific antibodies were included. Overall severity at diagnosis was defined by at least one of the following: severe muscle impairment, symptomatic interstitial lung disease (ILD), gastrointestinal (GI) vasculitis, myocarditis, severe skin ulceration or admission to an intensive care unit. Clinically inactive disease and remission were defined according to PRINTO group criteria and IMACS guidelines. RESULTS: Two hundred and one patients were included: 123 with aDM (≥18 years) and 78 with jDM (

Fields of Study & Subjects

Inflammatory Myopathies and Dermatomyositis Parkinson's Disease and Spinal Disorders Muscle and Compartmental Disorders

Publication details

Journal / source
Lara D. Veeken
Publisher
Oxford University Press (OUP)
Volume
65
Issue
2
Publication date
21 January 2026
Language
EN