Association of accelerometer-measured physical activity patterns with cardiovascular diseases and mortality in people with osteoarthritis

OBJECTIVE: To explore the associations between accelerometer-measured physical activity patterns and cardiovascular diseases (CVD), CVD-cause mortality and all-cause mortality in people with osteoarthritis (OA). METHODS: OA participants from the UK biobank with ≥36 h of accelerometer data, collected over one-week, were analysed. Moderate to vigorous physical activity (MVPA) patterns were classified as: 'weekend warriors' (≥150 min/week, >50% on 1-2 days), active regular (>150 min/week) or inactive (30 or those aged over 60. CONCLUSION: Engaging in a weekend warrior pattern may confer unique survival benefits for OA patients, especially among older adults and those with obesity. LPA may have dose-dependent protective effects for CVD and mortality risk in OA patients.