Poly(ADP-ribose) as a dynamic regulator of biomolecular condensates in cellular stress and signaling

2026 Dataset

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DOI: 10.1096/phase2026.s05.p03
Cited by: 0

Abstract

Poly(ADP-ribose) (PAR) is a dynamic, RNA-like protein modification that plays essential roles in DNA damage repair, stress responses, RNA metabolism, and cell-cycle regulation. The therapeutic success of PAR synthesis inhibitors (PARP inhibitors) in breast, ovarian, and prostate cancers underscores PAR’s clinical importance.

Fields of Study & Subjects

PARP inhibition in cancer therapy RNA Research and Splicing DNA Repair Mechanisms

Publication details

Publication date
24 February 2026
Language
EN
Document type
Dataset