An integrated discovery platform for targeting aberrant biomolecular phase transitions in neurodegenerative disorders and cancer

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Abstract

Aberrant phase transitions of biomolecular condensates are increasingly recognized as fundamental drivers of cellular dysfunction across cancer and neurodegeneration. Pathological condensate states can amplify transcriptional noise, mislocalize regulatory cofactors, and enforce maladaptive gene expression or protein homeostasis programs.

Fields of Study & Subjects

RNA Research and Splicing Genomics and Chromatin Dynamics Cancer-related molecular mechanisms research

Publication details

Publication date
24 February 2026
Language
EN
Document type
Dataset