Urodynamic predictors of daytime and nighttime urinary incontinence in FloRIN and Padua intracorporeal robotic neobladders: Results from two tertiary-care centers at mid-term follow-up

Background: Functional results of intracorporeal orthotopic ileal neobladders (iOINs) may vary depending on the selected neobladder technique. Standardization in reporting continence outcomes is lacking, as objective measurements based on urodynamic assessment remain limited. The aim of this series was to identify urodynamic predictors of daytime and nighttime urinary incontinence for robotic iOINs performed at 2 high-volume centers. Materials and methods: We retrospectively pooled data from two prospectively maintained institutional robot-assisted radical cystectomy databases covering the period from June 2017 to May 2023. The pooled dataset was queried to identify patients who underwent iOIN reconstruction and completed urodynamic evaluation, yielding a final study population of 94 patients. Baseline data and complete urodynamic profiles were collected. Urodynamic assessment was performed between 6 and 9 months after surgery. Frequencies and proportions were reported for categorical variables, while medians and interquartile ranges were reported for continuous variables. Univariable and multivariable logistic regression analyses were used to identify predictors of daytime and nighttime urinary incontinence at last follow-up. Multicollinearity among covariates initially considered for multivariable modeling was assessed using variance inflation factor analysis. A 2-sided p < 0.05 was considered statistically significant. Results: Overall, at a median follow-up of 25 months (interquartile range, 15.5–37.5), 94 patients achieved a complete urodynamic evaluation. On multivariable analysis, female gender (OR, 4.14; 95% CI, 1.37–12.5; p = 0.01) was the only independent predictor of daytime urinary incontinence, whereas cystometric capacity