Organ Preservation in Rectal Cancer Management: A Prospective GRECCAR Snapshot Study

Diseases of the Colon & Rectum 2026

View at publisher
Authors: Barbara Noiret, Gilles Manceau, Benjamı́n Fernández, Philippe Rouanet, Étienne Buscail, Bertrand Trilling, Hélène Meillat, J Lefevre, G. Meurette, Stephanie Benoist, Mehdi Karoui, Nicolas Peru
+19 more Léon Maggiori, Aurélien Venara, Mehdi Ouaissi, Dahbia Djelil, Adeline Germain, Eddy Cotte, Charles Sabbagh, Simone Manfredelli, Jean Jacques Tuech, Laura Beyer-Berjot, Arnaud Alves, Diane Mege, Frédéric Marchal, Jean Michel Fabre, Constance C Houlzé-Laroye, Christophe Taoum, Michel Rivoire, Quentin Denost, On behalf the GRECCAR group
DOI: 10.1097/dcr.0000000000004206
Cited by: 1
References: 29

Abstract

BACKGROUND: Organ preservation strategies, including watch and wait and local excision, are increasingly adopted in rectal cancer management. Total neoadjuvant therapy improves complete response rates, potentially expanding organ preservation indications. OBJECTIVE: This study aims to evaluate the real-world implementation of organ preservation strategies and short-term oncologic outcomes in patients with nonmetastatic mid- and low-rectal cancer in France. DESIGN: Prospective, multicenter, observational cohort study. SETTINGS: Twenty-seven French Groupe de RECherche sur le CAncer ColoRectal centers were included. PATIENTS: Patients with biopsy-proven, nonmetastatic rectal adenocarcinoma (

Fields of Study & Subjects

Colorectal Cancer Surgical Treatments Colorectal and Anal Carcinomas Stoma care and complications

Publication details

Journal / source
Diseases of the Colon & Rectum
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
69
Issue
7
Pages
1870–1879
Publication date
29 April 2026
Language
EN