Importance of changes in body mass index from adolescence to middle age as a risk factor for osteoporosis: the Japan Nurses’ Health Study
Abstract
OBJECTIVE: To investigate the association between changes in body mass index (BMI) from adolescence to middle age and osteoporosis risk among participants in the Japan Nurses' Health Study (JNHS), a nationwide prospective cohort study. METHODS: Data were reviewed for 15,019 participants in the JNHS. After excluding 6,511 participants aged below 40 years or diagnosed with osteoporosis at baseline, 8,508 participants were included. The mean age at baseline was 47.5±5.4 years, and the mean follow-up period was 15.5±6.3 years. Low body weight (L) was defined as BMI
Fields of Study & Subjects
Bone health and osteoporosis research
Diabetes
Cardiovascular Risks
and Lipoproteins
Bone Metabolism and Diseases
Publication details
- Journal / source
- Menopause The Journal of The North American Menopause Society
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Volume
- 33
- Issue
- 7
- Pages
- 767–774
- Publication date
- 27 January 2026
- Language
- EN