4D Lips Technique Based on Anatomy for Naturalization

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Authors: Melina Kichler, Marta Barros, Carolina de Freitas, RENATA CRISTINA TEIXEIRA PINTO VIANA, Marcelle Nogueira, Maria Bussade
Cited by: 1
References: 15

Abstract

Background: Lip augmentation has become a cornerstone of aesthetic procedures, particularly among younger patients seeking to enhance their natural lip features. A precise anatomical approach is essential to achieve balanced, natural-looking results while minimizing the risk of complications. This study introduced the 4D Lips technique, a multiphasic hyaluronic acid filler method designed to enhance lip shape while respecting anatomical landmarks. The technique is guided by 4 fundamental principles-dimension, distribution, dynamics, and desire-to ensure harmonious and individualized outcomes. Methods: Ten female patients underwent lip augmentation using a combination of subtechniques, including tubercle marking, vertical elongation, and vermilion border eversion. Two hyaluronic acid fillers with distinct viscoelastic properties were used: one with medium G' for structural support and another with low G' for contour refinement. Patient satisfaction and safety outcomes were systematically evaluated. Results: All patients reported satisfaction with the natural appearance of their enhanced lips. Mild and transient side effects, such as swelling, were observed and resolved spontaneously within a few days. No major complications were recorded. The structured, anatomy-based approach allowed for precise volumization, refined contouring, and preservation of natural lip dynamics. Conclusions: The 4D Lips technique underscores the value of an anatomy-informed and personalized approach to lip augmentation. By combining structural enhancement with a patient-centered perspective, this method achieves high satisfaction rates and a favorable safety profile. Nonetheless, the limitations of the study, including the small sample size, absence of a control group, and lack of long-term follow-up, warrant further investigation to validate these findings.

Fields of Study & Subjects

Facial Rejuvenation and Surgery Techniques Nasal Surgery and Airway Studies Reconstructive Facial Surgery Techniques

Publication details

Journal / source
Plastic & Reconstructive Surgery Global Open
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
14
Issue
1
Pages
e7270–e7270
Publication date
1 January 2026
Language
EN