Treatment and Prevention of Traumatic Eyebrow Cicatricial Alopecia With Stem Cell Growth Serum

Up to 16.6% of facial lacerations involve the eyebrows, and regional scarring often results in hair loss known as cicatricial alopecia (CA). Secondary CA following eyebrow lacerations is often irreversible, resulting in poor aesthetic outcomes and psychological distress. The current gold standard for treating CA is hair transplantation, but this is a painful and invasive procedure. We present 2 cases of patients who experienced eyebrow lacerations, 1 with chronic secondary CA and the other in the setting of acute facial trauma without eyebrow CA. Serial daily topical application of stem cell serum (Calecim) was commenced for both patients. Following 6 months of treatment, the patient with chronic secondary CA experienced regrowth of eyebrow hair, whereas the patient treated earlier retained their eyebrow hair and did not develop secondary CA. We propose stem cell serum as an effective, noninvasive treatment option for patients with chronic secondary CA to aid in hair regrowth. Furthermore, stem cell serum could be considered as an early treatment in acute eyebrow trauma for the prevention of CA development and hair retention.