Corneal Stromal Thinning and Posterior Irregularity After DMEK: Clinical Observations and Biophysical Hypotheses

Cornea 2026 Open access

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Authors: Alfredo Borgia, Matteo Airaldi, Sabrina Vaccaro, David Lockington, Filippo Lozza, Francesco Semeraro, Neethi Thathapudi, Sally Hayes, Phil Lewis, Stephen B. Kaye, Keith Meek, Vito Romano
DOI: 10.1097/ico.0000000000004084
Cited by: 1
References: 17

Abstract

PURPOSE: The aim of this study was to identify factors associated with significant postoperative stromal thinning in eyes undergoing Descemet membrane endothelial keratoplasty (DMEK). METHODS: This was a retrospective, multicenter interventional study. Eyes that underwent DMEK at Royal Liverpool University Hospital (UK) and ASST Spedali Civili di Brescia (Italy) were included. Eyes were stratified into 2 groups based on the final central corneal thickness (CCT):

Fields of Study & Subjects

Corneal surgery and disorders Corneal Surgery and Treatments Glaucoma and retinal disorders

Publication details

Journal / source
Cornea
Publisher
Ovid Technologies (Wolters Kluwer Health)
Publication date
27 January 2026
Language
EN