Reliability of RSV Antigen Diagnostic Tests in the Presence of Nirsevimab

The Pediatric Infectious Disease Journal 2026 Open access

Read full text
Authors: Sarah R Sincero, Kelly Ann Mahool, Emma C Schaefer, Carolina S. Caceres, Elizabeth J. Kelly, Deidre E. Wilkins, Kevin M. Tuffy
DOI: 10.1097/inf.0000000000005119
Cited by: 0
References: 18

Abstract

BACKGROUND: Nirsevimab is approved for the prevention of respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. Although nucleic acid detection by polymerase chain reaction is primarily utilized for the clinical diagnosis of RSV, antigen detection is still routinely used and primarily relies on direct interaction with the RSV F protein in patient nasal samples. While expected monoclonal antibody (mAb) levels in nasal samples are typically

Fields of Study & Subjects

Respiratory viral infections research SARS-CoV-2 detection and testing Virology and Viral Diseases

Publication details

Journal / source
The Pediatric Infectious Disease Journal
Volume
45
Issue
6
Pages
549–553
Publication date
6 January 2026
Language
EN