Timing of endoscopic retrograde cholangiopancreatography for management of bile leaks after cholecystectomy: A systematic review

Medicine 2026 Open access

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Authors: Tirath Daishikbhai Patel, Muhammad Farhan, Maral Daneshpazhouh, Aws Raid, Ariana Seyfi, Joel Jayan Peniel, Dima Alfarhan, Abdulaziz Sobhi, Mariyam M. Kuznetsova, Fadila Shuaibu Bello, Abdullatif Nasser Alatta, Abdul Basit Rasheed
+2 more Muhammad Hashir Nazir, Malik Abdullah Rasheed
DOI: 10.1097/md.0000000000047039
Cited by: 0
References: 19

Abstract

BACKGROUND: The optimal timing of endoscopic retrograde cholangiopancreatography (ERCP) for managing bile leaks after cholecystectomy remains unclear. This systematic review evaluates how ERCP timing affects clinical outcomes in adults with post-cholecystectomy bile leaks. METHODS: We included randomized controlled trials and cohort or case-control studies of adults (≥18 years) undergoing ERCP for bile leaks after cholecystectomy, comparing outcomes by timing of intervention. Exclusion criteria were case series (3 days: 16.7%) compared to emergent/urgent (

Fields of Study & Subjects

Gallbladder and Bile Duct Disorders Esophageal and GI Pathology Pancreatic and Hepatic Oncology Research

Publication details

Journal / source
Medicine
Volume
105
Issue
2
Pages
e47039–e47039
Publication date
9 January 2026
Language
EN