Past, present, and future of immunotherapy research in liver neoplasms: A bibliometric and visualization analysis

Liver neoplasms seriously threaten the lives and health of people worldwide and immunotherapies have shown remarkable therapeutic improvements in treating liver neoplasms in recent years. This study aims to provide a summary of the current state of research, key discoveries, and next directions in the field of liver neoplasms immunotherapy using bibliometrics. Researches search and data collection from Web of Science Core Collection. Calculations and visualizations were performed using Microsoft Excel, CiteSpace. For the previous 10 years (2014-2024), we identified 1663 English articles about immunotherapy for liver neoplasms, and that the number of articles increased more quickly after 2021. China, the Chinese Academy of Sciences, and Greten, Tim F are the country, institution, and writer with the most publications. The most cited reference was published by Finn RS in 2020. After 2021, people are paying more and more attention to liver neoplasms. There is a direct relationship between the incidence of liver neoplasms and the number of papers published, but the relationship between developed and developing countries is not close. Some areas of intense investigation in this discipline are sorafenib, tumor microenvironment, t cells, and dendritic cells.