Patchy Multifocal Bone Marrow Disease in a Young Adult Male With Acute Lymphoblastic Leukemia
Abstract
A diagnosis of acute lymphoblastic leukemia (ALL) rarely relies on magnetic resonance imaging (MRI) or positron emission tomography/computed tomography (PET/CT).However, patchy, multifocal bone marrow (BM) disease, a rare manifestation of ALL, can be diagnostically challenging since marrow infiltration is not uniform and may potentially be missed during a standard BM biopsy without guidance from imaging modalities.In this article, we will review the course of a young adult male who presented with patchy multifocal BM disease due to relapsed B-ALL, ultimately discovered on MRIs of multiple extremities, and confirmed through multiple, repeated BM biopsies.His disease response to chemotherapy was monitored with PET/CT, and he ultimately underwent a bone marrow transplant (BMT).
Fields of Study & Subjects
Bone and Joint Diseases
Acute Lymphoblastic Leukemia research
Acute Myeloid Leukemia Research
Publication details
- Journal / source
- Journal of Pediatric Hematology/Oncology
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Volume
- 48
- Issue
- 5
- Pages
- 259–260
- Publication date
- 20 May 2026
- Language
- EN