Validating HIV Viral Suppression Threshold Adjustments for Comparable Estimates Using Data From Nationally Representative Household Surveys in Sub-Saharan Africa

JAIDS Journal of Acquired Immune Deficiency Syndromes 2026 Open access

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Authors: Olanrewaju Edun, Lucy Okell, Timothy M Wolock, Eline L. Korenromp, Leigh Francis Johnson, Jeffrey W. Eaton
DOI: 10.1097/qai.0000000000003878
Cited by: 0
References: 21

Abstract

INTRODUCTION: To enable comparable global assessments of viral load suppression (VLS) among people living with HIV on antiretroviral therapy, the Joint United Nations Programme on HIV/AIDS applies a model to adjust VLS estimates reported at different thresholds to a common viral load ≤1000 copies/mL definition. We assessed performance of the current reverse Weibull model and alternatives using survey data from sub-Saharan Africa. METHODS: Using data from 21 Population-based HIV Impact Assessment surveys in 16 sub-Saharan African countries (2015-2022), we assessed 6 models (Weibull, reverse Weibull, Pareto, Fréchet, gamma, and lognormal) in adjusting VLS reported at viral load

Fields of Study & Subjects

HIV/AIDS Research and Interventions HIV/AIDS drug development and treatment HIV Drug Use Sexual Risk

Publication details

Journal / source
JAIDS Journal of Acquired Immune Deficiency Syndromes
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
101
Issue
8
Pages
827–835
Publication date
15 April 2026
Language
EN