Hollow viscus perforation secondary to brucellosis: a rare case report

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Authors: Rukma Raj Kafle, Rakshya Arun Kandel, Ashish Kc, Dhruba Kadel, Suyesh Shrestha, Chandan Shah
Cited by: 0
References: 20

Abstract

Introduction: Brucellosis, a zoonotic infection, rarely causes hollow viscus perforation. This case highlights ileal perforation in a patient with pre-diagnosed brucellosis, which reinforces the importance of early surgical evaluation in an acute abdomen. Presentation of Case: A young male with confirmed brucellosis (positive IgM serology) presented with fever and arthralgia. On day 2 of admission, he developed sudden severe abdominal pain, guarding, and rigidity. Imaging revealed pneumoperitoneum, prompting emergency laparotomy, which identified an ileal perforation. Wedge resection and anastomosis was performed, followed by combined antibiotics. Histopathology showed transmural inflammation with ulceration. The patient recovered fully postoperatively. Discussion: Brucellosis typically manifests with systemic symptoms; gastrointestinal involvement is uncommon. This case demonstrates ileal perforation without prior Gastrointestinal (GI) symptoms, likely due to ulceration. Early imaging and surgical intervention were crucial. In endemic regions, brucellosis should be considered in an acute abdomen with prolonged fever associated with arthralgia. Conclusion: Although rare, brucellosis can lead to life-threatening perforation. A high index of suspicion, prompt imaging, and timely surgery are vital for optimal outcomes, alongside prolonged antibiotic therapy.

Fields of Study & Subjects

Brucella: diagnosis epidemiology treatment Salmonella and Campylobacter epidemiology Diagnosis and treatment of tuberculosis

Publication details

Journal / source
International Journal of Surgery Case Reports
Volume
138
Issue
2
Pages
175–180
Publication date
9 January 2026
Language
EN