68Ga Trivehexin PET/CT in a Breast Carcinoma Patient With Distant Metastasis
Abstract
FDG PET CT has limitations in breast cancer due to its low tracer uptake in Grade 1 and 2 tumors, estrogen receptor positivity, lobular histology, and osteoblastic skeletal metastases. Trivehexin PET targets αvβ6 integrin, which is relatively specific for epithelial cancer cells. We present a case of a 67-year-old woman with recently diagnosed metastatic breast cancer. Trivehexin PET not only showed lesions with a higher target-to-background ratio compared with FDG PET but also depicted additional metastatic sites.
Fields of Study & Subjects
Medical Imaging Techniques and Applications
Radiopharmaceutical Chemistry and Applications
Peptidase Inhibition and Analysis
Publication details
- Journal / source
- Clinical Nuclear Medicine
- Volume
- 51
- Issue
- 8
- Pages
- e598–e600
- Publication date
- 30 January 2026
- Language
- EN