A Rare Linitis Plastica Manifestation of Esophageal Squamous Cell Carcinoma With Diffuse Gastric Metastasis Revealed by 18F-FDG PET/CT
Abstract
Diffuse gastric metastasis of esophageal squamous cell carcinoma (SCC) manifested as linitis plastica is extremely rare. A 49-year-old man complained of postprandial vomiting and epigastric colicky pain, and biopsy indicated mucosal inflammation. 18F-FDG PET/CT revealed diffuse wall thickening of mid-to-lower esophagus and diffuse gastric wall thickening accompanied by mediastinal lymph node, perigastric, and peripancreatic lesions with intense FDG accumulation. Malignancy of mid-to-lower esophagus and linitis plastica accompanied by lymph node, perigastric, and peripancreatic metastases was suspected. Biopsies of multiple sites of esophagus and stomach confirmed SCC. 18F-FDG PET/CT is instrumental for evaluating rare metastasis of esophageal SCC and guiding biopsy.
Fields of Study & Subjects
Esophageal Cancer Research and Treatment
Metastasis and carcinoma case studies
Esophageal and GI Pathology
Publication details
- Journal / source
- Clinical Nuclear Medicine
- Volume
- 51
- Issue
- 3
- Pages
- 235–236
- Publication date
- 3 February 2026
- Language
- EN