18F-FDG PET/CT Findings in a Case of Primary Leptomeningeal Melanomatosis With Diastematomyelia
Abstract
Primary leptomeningeal melanomatosis is a rare and aggressive variant of primary central nervous system melanoma. Diagnosis is often challenging due to nonspecific radiologic features. We hereby report the 18F-FDG PET/CT and MRI findings in a case of primary leptomeningeal melanomatosis in a 47-year-old woman with a previously unidentified diastematomyelia. Spinal MRI showed diffuse abnormal signal. 18F-FDG PET/CT showed hypermetabolism most notably in the lumbar and caudal portion of the spinal cord, which was helpful to identify an appropriate site for biopsy.
Fields of Study & Subjects
Cutaneous Melanoma Detection and Management
Medical Imaging Techniques and Applications
Brain Metastases and Treatment
Publication details
- Journal / source
- Clinical Nuclear Medicine
- Volume
- 51
- Issue
- 3
- Pages
- 237–239
- Publication date
- 3 February 2026
- Language
- EN