Incidental 18F-Flortaucipir Uptake in Pituitary Macroadenoma
Abstract
A 73-year-old woman with over 2 years of progressive memory decline underwent amyloid PET/CT ( 18 F-florbetaben) and tau PET/CT ( 18 F-flortaucipir) imaging for suspected Alzheimer disease (AD). This series of examinations confirmed the diagnosis of AD. Unexpectedly, a pituitary macroadenoma with significant 18 F-flortaucipir uptake was revealed, which might represent another instance of off-target binding.
Fields of Study & Subjects
Pituitary Gland Disorders and Treatments
Alzheimer's disease research and treatments
Medical Imaging Techniques and Applications
Publication details
- Journal / source
- Clinical Nuclear Medicine
- Volume
- 51
- Issue
- 8
- Pages
- e706–e708
- Publication date
- 22 January 2026
- Language
- EN