Radioactive Distribution Patterns of [68Ga]Ga-FAPI-04 in Primary Hepatocellular Carcinoma

Clinical Nuclear Medicine 2026

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Authors: Dongling Zhu, Yuankai Zhu, Sijuan Zou, Shuang Song, Qingjian Dong, Dong Kuang, Xiaohua Zhu
DOI: 10.1097/rlu.0000000000006345
Cited by: 1
References: 21

Abstract

PURPOSE: To evaluate the radioactive distribution patterns of [ 68 Ga]Ga-FAPI-04 in primary hepatocellular carcinoma (HCC). METHODS: Twenty-three primary HCC patients (26 lesions) from a prospective trial (ChiCTR2000039099) underwent both [ 18 F]FDG and [ 68 Ga]Ga-FAPI-04 PET/CT within 1 week. Uptake at tumor margins versus centers was compared. RESULTS: FAPI-04 uptake was significantly higher at tumor margins than centers (SUVmax, P

Fields of Study & Subjects

Peptidase Inhibition and Analysis Heat shock proteins research Superconductivity in MgB2 and Alloys

Publication details

Journal / source
Clinical Nuclear Medicine
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
51
Issue
4
Pages
320–324
Publication date
2 February 2026
Language
EN