68GA-DOTA-TATE PET/CT in the Assessment of Cranial and Spinal Hypertrophic Pachymeningitis

Clinical Nuclear Medicine 2026

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Authors: Emine Göknur Işık, Edanur Topal, Mehmet Barbüroğlu, Serkan Kuyumcu, Yasemin Şanlı
DOI: 10.1097/rlu.0000000000006347
Cited by: 0
References: 6

Abstract

Hypertrophic pachymeningitis is an uncommon disorder characterized by chronic inflammation and thickening of the dura mater, which can be idiopathic or secondary to autoimmune or infectious causes such as sarcoidosis, IgG4-related disease, tuberculosis, or syphilis. We report the case of a patient with a preliminary diagnosis of pachymeningitis in whom 68 Ga-DOTA-TATE PET/CT demonstrated intense radiotracer uptake corresponding to dural thickening on MRI. The findings suggest the potential role of somatostatin receptor imaging in assessing disease extent and activity, and in differentiating inflammatory pachymeningitis from neoplastic or infectious mimics.

Fields of Study & Subjects

Vasculitis and related conditions IgG4-Related and Inflammatory Diseases Pituitary Gland Disorders and Treatments

Publication details

Journal / source
Clinical Nuclear Medicine
Volume
51
Issue
5
Pages
444–445
Publication date
2 February 2026
Language
EN