Lung Metastases from Meningioma Diagnosed on Whole Body 68Ga-DOTATOC PET/CT and Successfully Targeted With 177Lu-DOTATATE
Abstract
Metastases from meningioma are very rare and occur predominantly in WHO grade II and III tumors, with the lungs being the most common site. The increasing use of 68Ga-DOTA-peptides PET/CT has improved the detection of primary and secondary tumor sites. This imaging modality, evaluating the tumor expression of somatostatin receptors (SSTR), not only refines the diagnostic accuracy but also can guide a subsequent peptide receptor radionuclide therapy (PRRT). We report a case of meningioma brain tumor becoming refractory after initial neurosurgery and stereotactic radiotherapy. Meningioma has progressed to lung metastases displaying high expression of SSTR, and hence suitable for PRRT.
Fields of Study & Subjects
Meningioma and schwannoma management
Neuroendocrine Tumor Research Advances
Radiopharmaceutical Chemistry and Applications
Publication details
- Journal / source
- Clinical Nuclear Medicine
- Volume
- 51
- Issue
- 4
- Pages
- 335–337
- Publication date
- 2 March 2026
- Language
- EN