Unexpected 123I FP-CIT (DaT SCAN) Uptake in Palpebral Conjunctival Melanoma
Abstract
A 60-year-old woman underwent evaluation for a 6-year history of Parkinsonism. One year earlier, she had been diagnosed with malignant melanoma of the left palpebral conjunctiva, which recurred despite treatment. For the assessment of Parkinson disease, 123 I FP-CIT and Tc-99m ECD SPECT were performed. Unexpectedly, intense 123 I FP-CIT uptake was observed in the left eyelid lesion, whereas 99m Tc-ECD showed no uptake. CT and MRI demonstrated a corresponding mass consistent with recurrent malignant melanoma. This first report underscores the need to recognize extrastriatal tracer uptake.
Fields of Study & Subjects
Medical Imaging Techniques and Applications
Ocular Oncology and Treatments
Parkinson's Disease Mechanisms and Treatments
Publication details
- Journal / source
- Clinical Nuclear Medicine
- Volume
- 51
- Issue
- 6
- Pages
- 532–533
- Publication date
- 5 February 2026
- Language
- EN