“Hot Liver” in Hepar Lobatum Carcinomatosum on [18F]FDG PET-CT

Clinical Nuclear Medicine 2026 Open access

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Authors: Maxime Guedj, Ondine Dufour, Emmanuelle Charafe‐Jauffret, Jacques Ewald, Nathalie Charrier
DOI: 10.1097/rlu.0000000000006390
Cited by: 0
References: 10

Abstract

A 54-year-old woman underwent [ 18 F] FDG PET/CT for assessment of a voluminous ascites with an infiltrating lesion on the left breast at clinical examination. PET-CT revealed a large left breast lesion with homolateral axillary lymph nodes and a left iliac lytic bone lesion, but also hepatomegaly with diffuse and extensive uptake with brain and renal hypometabolism. The result suggest an hepar lobatum carcinomatosum with sequestration of the radiotracer in the liver with a reduction of the background physiological activity. This "hot liver aspect" means being cautious about the risk of a false-negative lesion at staging.

Fields of Study & Subjects

Medical Imaging Techniques and Applications Radiopharmaceutical Chemistry and Applications Metastasis and carcinoma case studies

Publication details

Journal / source
Clinical Nuclear Medicine
Volume
51
Issue
6
Pages
520–521
Publication date
20 February 2026
Language
EN