Extracranial Metastases From FET-CREB Fusion-positive Intracranial Mesenchymal Tumor on FDG PET/CT

Clinical Nuclear Medicine 2026

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Authors: Jiawen Wang, Sihan He, Bingbing Ran, Aisheng Dong, Hongguang Zhao
DOI: 10.1097/rlu.0000000000006459
Cited by: 2
References: 15

Abstract

FET-CREB fusion-positive intracranial mesenchymal tumor is a newly recognized provisional tumor type. Usefulness of FDG PET/CT in the management of this tumor is rarely reported. We describe FDG PET/CT findings in a case of FET-CREB fusion-positive intracranial mesenchymal tumor with metachronous extracranial metastases to the mediastinum, mesentery, and left Leg. The metastatic tumors showed mild to moderate FDG uptake. This case indicates that FET-CREB fusion-positive intracranial mesenchymal tumors can develop extracranial metastasis, and FDG PET/CT may be useful for detecting extracranial metastasis of this rare tumor.

Fields of Study & Subjects

Glioma Diagnosis and Treatment Brain Metastases and Treatment Medical Imaging Techniques and Applications

Publication details

Journal / source
Clinical Nuclear Medicine
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
51
Issue
8
Pages
735–737
Publication date
31 March 2026
Language
EN