Advancement of functional peptides: Promising candidates for antituberculosis therapeutics

Science of Traditional Chinese Medicine 2026 Open access

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Authors: Bojie Lin, Siqi Lin, Yang Jiayi, Xuanyu Yang, Shuhui Wang, Yiyu Liu, Q F Zhang, Jun-Fa Xu, Jiang Pi, Fan Yang
DOI: 10.1097/st9.0000000000000099
Cited by: 1
References: 142

Abstract

Tuberculosis (TB), a chronic infectious disease caused by Mycobacterium tuberculosis , is primarily airborne and remains a global health problem, especially in resource-limited countries and regions. The emergence of drug resistance in M. tuberculosis has rendered the existing means ineffective in the treatment of TB. Therefore, research in new therapeutic directions has become imperative. In this review, we outline functional peptides in terms of the mechanisms of action, anti-TB attempts, advantages and disadvantages, and latest advances, aiming to analyze the research progress in anti-TB peptides. Furthermore, we investigate the potential applications of bioactive compounds found in traditional Chinese Medicine within the context of peptides.

Fields of Study & Subjects

Antimicrobial Peptides and Activities Tuberculosis Research and Epidemiology Antimicrobial agents and applications

Publication details

Journal / source
Science of Traditional Chinese Medicine
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
4
Issue
1
Pages
24–32
Publication date
16 February 2026
Language
EN