Differences in Mortality by Donor Sex and Age in a Multinational Cohort of Liver Transplant Recipients

Transplantation Direct 2026 Open access

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Authors: Lauren T. Grinspan, X. Zhang, Mourad Dahhou, Caner Süsal, Bernd Döhler, Anette Melk, Amanda Vinson, Bethany J. Foster
DOI: 10.1097/txd.0000000000001912
Cited by: 2
References: 31

Abstract

Background: Prior studies assessing the association between donor sex and liver transplant outcomes showed conflicting results. We hypothesized that donor age, recipient sex, and time posttransplant modify the relationship between donor sex and mortality. Methods: First deceased donor liver transplant recipients 13 y or older recorded in the Scientific Registry of Transplant Recipients and the Collaborative Transplant Study (n = 198 856; 1988-2019) were studied. We used multivariable Cox models to estimate the association between donor sex and mortality, accounting for the modifying effects of recipient sex, donor age (13-44, 45-59, ≥60 y), and time posttransplant (

Fields of Study & Subjects

Organ Transplantation Techniques and Outcomes Renal Transplantation Outcomes and Treatments Organ Donation and Transplantation

Publication details

Journal / source
Transplantation Direct
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
12
Issue
3
Pages
e1912–e1912
Publication date
11 February 2026
Language
EN