External Validation of a Postoperative Renal Function Predictive Model Following Partial Nephrectomy

INTRODUCTION: ) of 0.66, with 82% of patients having a postoperative estimated GFR within 30% of the predicted GFR (P30). The purpose of this study was to assess its performance in patients enrolled in the renal hypothermia trial. METHODS: , calibration slope, calibration plot, and precision (P10: within 10%; P20: within 20%; and P30: within 30%). RESULTS: was 0.67. The model was reasonably precise with 73 patients within 10% of predicted GFR (P10 = 41.7%), 129 within 20% of predicted GFR (P20 = 73.7%), and 156 within 30% of predicted GFR (P30 = 89.1%). The calibration slope was 1.04, with good calibration across a wide range of baseline renal function. Limitations include modest sample size, predominantly Caucasian patients, and restriction to open PN, limiting generalizability. CONCLUSIONS: Tc-DTPA plasma clearance. This model can be used as a component of informed decision-making when counseling patients on expected outcomes following partial nephrectomy.