Automated serial electron diffraction: implementation in LibraEDT and its applications
Abstract
Serial electron diffraction (SerialED) offers an effective route for structure determination of beam-sensitive materials, yet its adoption has been limited by the practical challenges of manual acquisition and the handling of large datasets. In this work, we introduce the implementation of continuous SerialED, also known as stage-scanning SerialED, within LibraEDT for unsupervised data collection. To illustrate its practicality, SerialED datasets were collected with and without precession and later processed with minimal additional effort, showing that the acquisition strategy is compatible with standard data processing tools.
Fields of Study & Subjects
Advanced Electron Microscopy Techniques and Applications
Enzyme Structure and Function
Crystallography and Radiation Phenomena
Publication details
- Journal / source
- Journal of Applied Crystallography
- Publisher
- International Union of Crystallography (IUCr)
- Volume
- 59
- Issue
- 3
- Pages
- 858–868
- Publication date
- 7 May 2026
- Language
- EN