Crystal structure and Hirshfeld surface analysis of 1-(2-chloroacetyl)-3-methyl-2,6-bis(4-methylphenyl)piperidin-4-one
Abstract
In the crystal structure of the title compound, C 22 H 24 ClNO 2 , the piperidine ring adopts a boat conformation. Intra- and intermolecular C—H...Cl hydrogen bonds are observed. The intermolecular interactions were quantified and analysed using Hirshfeld surface analysis, revealing that H...H interactions contribute most to the crystal packing (56.1%).
Fields of Study & Subjects
Crystal structures of chemical compounds
Crystallography and molecular interactions
Molecular Sensors and Ion Detection
Publication details
- Journal / source
- Acta Crystallographica Section E Crystallographic Communications
- Volume
- 82
- Issue
- 2
- Pages
- 152–155
- Publication date
- 7 January 2026
- Language
- EN