A Secure and Interoperable Big Data Platform for AI-Driven Healthcare Solutions: Insights From the GATEKEEPER Project

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Authors: Christian Temporale, E. De Salvo, Eugenio Gaeta, Miguel Rujas, Laura Lopez-Perez, Muhammad Salman Haleem, Vasilis Aidonis, Eleni I. Georga, Dimitrios Fotiadis, Leandro Pecchia, Giuseppe Fico
Cited by: 2
References: 63

Abstract

Digital innovation in the healthcare industry is transforming the delivery of healthcare services and enhancing their inherent capabilities. At the heart of this revolutionary process are healthcare data platforms, which enable organizations to aggregate and leverage patient data. However, the application of Big Data Analytics (BDA) and Artificial Intelligence (AI) in this sector presents important challenges, including technical, ethical, social, economic, organizational, and political-legal issues. The multi-disciplinary and cross-sectoral nature of the health and life-science contexts introduces barriers to communication and data sharing among various stakeholders, and exacerbates technical challenges such as interoperability, data protection, security management, compliance with laws and regulations, and support for AI applications. This paper presents the AI Big Data Platform (BDP) for healthcare, developed within the GATEKEEPER project, addressing the challenges associated with implementing state-of-the-art solutions in the healthcare context. This AI BDP facilitates the extraction of value from big volumes of heterogeneous and sensitive patient data while preserving privacy. It provides key features in interoperability, end-to-end security, multitenancy, and support for computationally intensive AI workloads. The AI Big Data Platform’s services are utilized by 8 GATEKEEPER pilots, deployed into 7 different countries, to implement 9 Reference Use Cases (RUC) 1, and involving approximately 200 users.

Fields of Study & Subjects

Artificial Intelligence in Healthcare and Education Artificial Intelligence in Healthcare Electronic Health Records Systems

Publication details

Journal / source
IEEE Access
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Volume
14
Pages
16389–16405
Publication date
1 January 2026
Language
EN