A Survey of Domain-Specific Fine-Tuned Large Language Models

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Authors: Paria Sarzaeim, Akramul Azim, Gary Bauer, Masoud Makrehchi
Cited by: 6
References: 101

Abstract

The advancement of large language models (LLMs), such as GPT-3, BERT, and Llama, has introduced a new era in natural language processing (NLP) as they have demonstrated exceptional capabilities across diverse tasks. Fine-tuning these LLMs with domain-specific data has become a popular practice, particularly in domains like education, law, medicine, and software development. This process not only empowers LLMs with domain knowledge but also enhances their capabilities by addressing issues such as reliability and reducing the chance of hallucination. This survey examines a range of domain-specific fine-tuned models by highlighting their unique characteristics, enhancements in performance, and the challenges they address, including the demand for extensive computational resources. Furthermore, we explore the fine-tuning methodologies, including instruction tuning used in the development of these models, and ultimately, inform future research on the existing gaps and how to enhance the effective application of LLMs across diverse domains.

Fields of Study & Subjects

Artificial Intelligence in Healthcare and Education Topic Modeling Machine Learning in Healthcare

Publication details

Journal / source
IEEE Access
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Volume
14
Pages
48407–48433
Publication date
1 January 2026
Language
EN