MedFact-R1: Towards Factual Medical Reasoning Via Pseudo-Label Augmentation
Abstract
Ensuring factual consistency and reliable reasoning remains a critical challenge for medical vision-language models. We introduce MedFact-R1, a two-stage framework that integrates external knowledge grounding with reinforcement learning to improve the factual medical reasoning. The first stage uses pseudo-label supervised fine-tuning (SFT) to incorporate external factual expertise; while the second stage applies Group Relative Policy Optimization (GRPO) with four tailored factual reward signals to encourage self-consistent reasoning at deployment time without relying on external RAG. Across three public medical QA benchmarks, MedFact-R1 delivers up to 22.5% absolute improvement in factual accuracy over previous state-of-the-art methods. Ablation studies highlight the necessity of pseudo-label SFT cold start and validate the contribution of each GRPO reward, underscoring the synergy between knowledge grounding and RL-driven reasoning for trustworthy medical AI. Codes are released at https://github.com/Garfieldgengliang/MEDFACT-R1.
Fields of Study & Subjects
Multimodal Machine Learning Applications
Machine Learning in Healthcare
Topic Modeling
Publication details
- Journal / source
- ICASSP 2026 - 2026 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)
- Publisher
- IEEE
- Pages
- 7377–7381
- Publication date
- 21 April 2026
- Language
- EN