Multi-Domain Security for 6G ISAC: Challenges and Opportunities in Transportation

Integrated sensing and communication (ISAC) will be central to 6G-enabled transportation, providing both seamless connectivity and high-precision sensing. However, this tight integration exposes attack points not encountered in pure sensing and communication systems. In this article, we identify unique ISAC-induced security challenges and opportunities in three interrelated domains: cyber-physical (where manipulation of sensors and actuators can mislead perception and control), physical-layer (where over-the-air signals are vulnerable to spoofing and jamming) and protocol (where complex cryptographic protocols cannot detect lower-layer attacks). Building on these insights, we put forward a multi-domain security vision for 6G transportation and propose an integrated security framework that unifies protection across domains by leveraging existing ISAC measurements for lightweight cross-checks.