Rethinking Signaling Design for ISAC: From Pilot-Based to Payload-Based Sensing

Integrated Sensing and Communications (ISAC) is emerging as a key enabler for 6G networks, with signaling design at the core of its evolution. This paper reviews the paradigm shift of ISAC signaling designs from pilot-aided sensing to data payload-based approaches, with a particular focus on how these techniques can be realized within existing 5G New Radio (NR) structures. We commence with the reuse of pilots and reference signals that exploit existing 5G NR structures for sensing. Then, we extend to more advanced approaches that integrate the data payload through novel constellation shaping, modulation bases, and pulse shaping filters. We highlight the opportunities and tradeoffs that arise when extending sensing from sparse pilot and reference signal resources to the full communication frame, emphasizing how constellation properties and modulation choices directly determine sensing performance. To illustrate practical feasibility, a case study on sensing-assisted NR Vehicle-to-Infrastructure (V2I) networks demonstrates how exploiting both reference signals and payload echoes can reduce signaling overhead and enable proactive beam management and handover.