A Multifunctional Neural Probe with Drug Delivery Capability by 3D Printed Microfluidic Channel

IEEE International Conference on Micro Electro Mechanical Systems (MEMS) 2026

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Authors: Yuxing Pang, Chang Guo, Yuying Shao, Zhe Zhu Huang, Dongxu Ma, Jingquan Liu, Zhuo Huang, Zhihong Li
DOI: 10.1109/mems64181.2026.11419412
Cited by: 0
References: 12

Abstract

This paper presents a multifunctional neural probe capable of simultaneous drug delivery and electrophysiological signal recording in deep brain regions of mice. Utilizing 3D printing technology, the intricate microfluidic structures can be fabricated in a single step. Upon implantation into the mouse hippocampus, kainic acid (KA) is successfully delivered via the microfluidic channel to induce epilepsy, while corresponding waveforms are recorded. The proposed multifunctional neural probe is expected to offer a more customizable tool for complex biological experiments.

Fields of Study & Subjects

Neuroscience and Neural Engineering Microfluidic and Capillary Electrophoresis Applications Analog and Mixed-Signal Circuit Design

Publication details

Journal / source
IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages
447–450
Publication date
25 January 2026
Language
EN