Hybrid Fabrication of a Multi-Actuator Ingestible Capsule for Localized GI Drug Delivery

IEEE International Conference on Micro Electro Mechanical Systems (MEMS) 2026

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Authors: Joshua A. Levy, Nomin‐Erdene Oyunbaatar, Jude A. C. Stephen, Rehan M. Rao, Justin M. Stine, Luke A. Beardslee, Reza Ghodssi A
DOI: 10.1109/mems64181.2026.11419470
Cited by: 0
References: 10

Abstract

This work describes a hybrid-fabricated, multi-actuator ingestible capsule designed for localized drug delivery in the gastrointestinal (GI) tract. The capsule$(27 \text{mm} \times 10.6 ~\text{mm})$embeds flexible gold-polyimide microheaters with 3D-printed biocompatible structures and polyether ether ketone (PEEK) cantilevers carrying dissolvable microneedle payloads. Upon selective activation of individual actuators, localized heating melts an ethylene-vinyl acetate (EVA) adhesive layer, enabling rapid$(

Fields of Study & Subjects

Advanced Drug Delivery Systems Advancements in Transdermal Drug Delivery Advanced MEMS and NEMS Technologies

Publication details

Journal / source
IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages
550–553
Publication date
25 January 2026
Language
EN