Hybrid Thin Film Transistor-Micro Electrode/Micro Pillar Array Platform for Multimodal Electrophysiological and Contractility Analysis of Cardiomyocytes

IEEE International Conference on Micro Electro Mechanical Systems (MEMS) 2026 Open access

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Authors: Cecilia Beccari, Gilgueng Hwang, Satoshi Amaya, Fumihito Arai, Yoshio Mita, Roberto Raiteri, Agnès Tixier‐Mita
DOI: 10.1109/mems64181.2026.11419551
Cited by: 0
References: 8

Abstract

We present for the first time a hybrid platform combining a Thin-Film Transistor Microelectrode Array (TFT-MEA) and a Micro-Pillar Array (MPA) for simultaneous, label-free analysis of electrophysiological and contractile activity in cardiomyocytes. Validation with isoprenaline confirmed the system's sensitivity to pharmacological effects, supporting its use in drug screening and cardiotoxicity studies.

Fields of Study & Subjects

Neuroscience and Neural Engineering Tissue Engineering and Regenerative Medicine Cardiac electrophysiology and arrhythmias

Publication details

Journal / source
IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages
530–533
Publication date
25 January 2026
Language
EN