Anatomy-Guided Radiology Report Generation With Pathology-Aware Regional Prompts

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Authors: Yijian Gao, Dominic Marshall, Xiaodan Xing, Junzhi Ning, Congren Dai, Giorgos Papanastasiou, Guang Yang, Matthieu Komorowski
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Abstract

Goal:Radiology report generation holds significant potential to alleviate clinical workloads and streamline medical care. However, achieving high clinical accuracy remains challenging, as radiographs often feature intricate structures and subtle pathologies.Methods:To address these challenges, this work introduces an innovative approach that explicitly integrates anatomical and pathological information into report decoding by leveraging pathology-aware regional prompts. Specifically, we develop an anatomical region detector that extracts structured visual features from distinct anatomical areas, coupled with a novel multi-label pathology detector that identifies global abnormalities.Results:Our model demonstrates superior report generation performance in natural language generation and clinical efficacy, surpassing previous state-of-the-art methods. It achieved scores of 0.394 in BLEU-1, 0.302 in ROUGE-L, and 0.470 in F1, reflecting substantial improvements in both linguistic fluency and medical accuracy. Formal expert evaluations further affirmed the model's potential to elevate radiology practice.Conclusion: By integrating anatomical and pathological insights to emulate radiologists' workflow, our model achieves superior accuracy and clinical coherence of radiology reporting. It offers remarkable promise to support clinical decision-making and transform patient management.

Fields of Study & Subjects

Topic Modeling Biomedical Text Mining and Ontologies Natural Language Processing Techniques

Publication details

Journal / source
IEEE Open Journal of Engineering in Medicine and Biology
Volume
7
Pages
165–171
Publication date
1 January 2026
Language
EN