Haptic-Assisted Magnetic Navigation of Microswarm for Targeted Delivery in Dynamic Fluidic Environments

Microswarms face challenges in precise delivery within dynamic biological fluids due to fluid disturbances and limited operational intuitiveness. Current approaches insufficiently utilize the operator’s perceptual awareness and interactive decision-making capabilities, particularly in complex tasks that require a balance between flexibility and precision. In this study, we propose a haptic-assisted magnetic actuation control strategy, establishing a human-in-the-loop control framework. The haptic perception system provides the operator with haptic feedback reflecting the interactions between the microswarm and the environment. A real-time tracking system monitors the position and pattern of the controlled microswarm in remote environments, and transmits this information to the control system for decision-making. After characterizing the magnetic field parameters and magnetic nanoparticles, we have achieved real-time navigation and morphology modulation of the microswarm in dynamic flow conditions and three-dimensional (3D) space. Comparative experiments under various flow rate conditions demonstrate that the haptic-assisted strategy enhances microswarm control stability and precision across different flow regimes. Moreover, the human-machine collaboration mechanism improves delivery success rates (97%) under sudden disturbances compared to preprogrammed automated control and purely manual control, validating its potential for applications in complex biomedical scenarios. Our work provides a haptic-assisted microswarm control method in dynamic conditions, expanding an adaptive microswarm control strategy in complex biomedical environments.