Enhancing Knee Disease Diagnosis via Multi-View Graph Representation With Multi-Task Pre-Training

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Authors: Zixu Zhuang, Dongdong Chen, Sheng Wang, Kai Xuan, Xiangyu Zhao, Zhong Xue, Dinggang G. Shen, LiChi Zhang, Weiwu Yao, Qian Wang
Cited by: 0
References: 37

Abstract

Magnetic resonance imaging (MRI) is an indispensable tool for clinical knee examination, which often scans 2D stacked slices from multiple views. Radiologists typically locate lesion regions in one view, and then refer to other views to formulate a comprehensive diagnosis. However, existing computer-aided diagnosis methods fall short of identifying and fusing local regions in multi-view scans, leading to a decline in diagnostic performance and a heavy reliance on extensively annotated data. This paper introduces a novel framework that represents multi-view MRI scans as a knee graph, and conducts diagnosis using the proposed Knee Graph Network (KGNet). Moreover, KGNet is greatly enhanced by multi-task pre-training, which requires KGNet to reconstruct masked knee local patches and segment unmasked ones working alongside corresponding decoders. Experimental evaluations on public and in-house clinical datasets confirm that our framework outperforms existing approaches in diagnosing cartilage defects, anterior cruciate ligament tears, and knee abnormalities. In conclusion, our framework demonstrates the potential of enhancing knee disease diagnosis by representing multi-view MRI scans as a graph and employing multi-task pre-training in the graph network. The code is publicly available at https://github.com/zixuzhuang/KGNet.

Fields of Study & Subjects

Medical Imaging and Analysis Artificial Intelligence in Healthcare and Education Medical Image Segmentation Techniques

Publication details

Journal / source
IEEE Transactions on Medical Imaging
Volume
45
Issue
5
Pages
2493–2504
Publication date
3 February 2026
Language
EN