Geranium: Multimodal Retrieval of Genomics Data Visualizations

Read full text
Authors: Huyen N. Nguyen, Sehi L’Yi, Thomas Chris Smits, Shanghua Gao, Marinka Žitnik, Nils Gehlenborg
Cited by: 0
References: 57

Abstract

Effective visualization is essential for interpreting genomics data, yet researchers often face challenges in finding relevant, reusable examples. Existing tools offer limited support for searching the vast landscape of genomics visualizations, making the process of authoring new visualizations time-consuming and inefficient. To address this gap, we introduce Geranium, a data visualization retrieval system for searching and authoring genomics visualizations. Geranium supports multimodal retrieval, enabling users to query with images, text, or grammar-based specifications. Retrieved examples serve as scaffolds for authoring, providing templates that researchers can adapt with their own data, thereby streamlining the mechanics of visualization construction. Geranium integrates three embedding methods to combine specialized and general knowledge: grammar-based embeddings tailored to genomics visualizations, multimodal embeddings from a biomedical vision-language foundation model, and text embeddings from a fine-tuned large language model. For each visualization, we construct a multimodal representation that includes a Gosling specification, a pixel-based rendering, and natural language descriptions. We evaluate embedding strategies to maximize top-$k$k retrieval accuracy and conduct user studies with domain collaborators to gather feedback on usability. Our collection comprises 3,200 visualizations across 50 categories, ranging from single-view to coordinated multi-view designs and supporting applications from single-cell epigenomics to structural variation analysis.

Fields of Study & Subjects

Biomedical Text Mining and Ontologies

Publication details

Journal / source
IEEE Transactions on Visualization and Computer Graphics
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Volume
32
Issue
7
Pages
6447–6463
Publication date
13 April 2026
Language
EN