Challenges in establishing a link between THC exposure and cannabis use disorder

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Authors: Jakob Manthey, Anna Schranz, Jeffrey D. Wardell
Cited by: 1
References: 12

Abstract

Challenges in establishing a link between THC exposure and cannabis use disorder In low-risk use guidelines [1, 2], the frequency of cannabis use and the product potency (i.e.concentration of delta-9-tetrahydrocannabinol, THC) are considered key determinants for cannabis-attributable harm, most notably cannabis use disorder (CUD).Although the link between frequency of use and risk of CUD is well established and causally plausible [3], the same cannot yet be said for potency and CUD.

Fields of Study & Subjects

Cannabis and Cannabinoid Research Forensic Toxicology and Drug Analysis Substance Abuse Treatment and Outcomes

Publication details

Journal / source
Addiction
Publisher
Wiley
Publication date
18 February 2026
Language
EN