Multi‐Omics‐Based Biological Mechanisms for Childhood Allergen Sensitization Trajectories: COCOA Study

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Authors: Hea Young Oh, Eun Lee, Jeonghun Yeom, Hyun Ju Yoo, Seung Hwa Lee, So-Yeon Lee, Hyo‐Bin Kim, Song‐I Yang, Da Kyeong Lee, Jisun Yoon, Eom Ji Choi, Youn Ho Shin
+6 more Kangmo Ahn, Jihyun Kim, Dong In Suh, Ji Soo Park, Kyung Won Kim, Soo‐Jong Hong
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References: 5

Abstract

The datasets from this study are not publicly available due to ethical restrictions. Figure S1: The proportion of trajectories for allergic diseases according to sensitization trajectories. Figure S2: Different intensities in metabolites between Cluster 1 and Cluster 3. Table S1: General characteristics and comorbidities according to the sensitization trajectories. Table S2: Characteristics of the subjects absent from and involved in the multi-omics integration. Table S3: Functional annotation of proteins with varying intensities between the clusters. Table S4: Multivariable regression analysis between clinical markers and trihydroxyvitamin D. Table S5: Multivariable regression analysis between cord blood vitamin D and trihydroxyvitamin D at age 7. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Fields of Study & Subjects

Allergic Rhinitis and Sensitization Asthma and respiratory diseases Food Allergy and Anaphylaxis Research

Publication details

Journal / source
Allergy
Volume
81
Issue
8
Pages
2952–2955
Publication date
19 January 2026
Language
EN